BDBM21173 1,3-dipropyl-8-cyclopentylxanthine::8-cyclopentyl-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione::CHEMBL183::DPCPX::PD116948::[3H]DPCPX
SMILES CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCCC1
InChI Key InChIKey=FFBDFADSZUINTG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 61 hits for monomerid = 21173
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 56nMAssay Description:Binding affinity towards human Adenosine A2a receptor expressed in HEK293 cells using 6 nM [3H]CGS-21680More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Inhibitory activity against binding of [3H]-DPCPX to human A1 receptor (hA1) using competition binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 97nMAssay Description:Displacement of [3H]ZM241385 from human A2AR expressed in CHO cell membranes measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 129nMAssay Description:Displacement of [3H]-ZM 241385 binding to human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 129nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]ZM-241385 from human cloned adenosine A2A receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 144nMAssay Description:Binding affinity against adenosine A2 receptor in human striatal membranes using [3H]-CGS-21,680 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of [3H]ZM241385 from human Adenosine A2A receptor expressed in HeLa cells after 30 minsMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 157nMAssay Description:Displacement of [3H]MSX2 from rat adenosine A2A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of [3H]HZ241385 from human A2AAR expressed in HeLa cell membrane incubated for 30 mins by microbeta trilux scintillation counter analysi...More data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of [3H]ZM2421385 from adenosine A2A receptor expressed in human HeLa cell membranes incubated for 30 mins by scintillation counting meth...More data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement [3H]ZM241385 from adenosine A2A receptor in human HeLa cell membranes incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of [3H]4-(2-[7-amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol from human adenosine A2A receptor expressed ...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 157nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatum membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 157nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatal membrane after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 200nMAssay Description:Binding affinity against adenosine A2 receptor in bovine striatal membranes using [3H]-CGS-21,680 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 226nMAssay Description:Binding affinity for HA-tagged wild type human Adenosine A2A receptor (WT) using [3H]CGS-21680 as radioligand expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [125I]NECA from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H]NECA from human cloned adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Binding affinity to human adenosine A2a receptorMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H]NECA from cloned human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 291nMAssay Description:Binding affinity for HA-tagged mutant human Adenosine A2A receptor (H250N) using [3H]-CGS-21,680 as radioligand expressed in COS-7 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]CGS 21680 from adenosine A2A receptor in bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]NECA from human A2A adenosine receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cell membrane after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]CGS 21680 from adenosine A2A receptor in bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2a receptor of bovine striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2a receptor of bovine striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:The membranes prepared from CHO cells transfected with human adenosine A2A receptors were used in binding assays. Nonspecific binding was determined ...More data for this Ligand-Target Pair
Affinity DataKi: 337nM ΔG°: -8.82kcal/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (30 ug) were incubated at 25 °C for
90 min in 500 uL of binding buffer (50 mM Tris-HCl, 2 mm MgCl2, 2
units/mL ADA, ...More data for this Ligand-Target Pair
Affinity DataKi: 337nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2A receptor in bovine striatal membranes.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 340nMAssay Description:Displacement of [3H]-CGS- 21680 from adenosine A2a receptors of rat striatal membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 340nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Affinity to A2 adenosine receptor was measured by the displacement of [3H]-CGS- 21680 in bovine brain striatal membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 340nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in Wistar rat striatal membranesMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 470nMAssay Description:Inhibition of [3H]-MSX-2 binding to rat adenosine A2A receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Zeneca Pharmaceuticals
Curated by PDSP Ki Database
Affinity DataKi: 470nMAssay Description:Inhibition of [3H]MSX-2 binding to adenosine A2a receptorMore data for this Ligand-Target Pair